Corneal abscesses: Diagnostic and therapeutic difficulties about 180 cases

Research Area: Medicine Authors
Salma HASSINA* B BEKKAR Mohammed Amine KRICHENE Ihssane HASNAOUI Zahira HAZIL Loubna ROBBANA Youness AKKANOUR Louay SERGHINI El Hassan ABDALAH
Ophthalmology B, Ibn-Sina University Hospital RABAT MOROCCO

Abstract
Corneal abscesses, whether bacterial, fungal or viral in origin, represent a major public health challenge, and can lead to significant vision loss through corneal scarring or surface irregularities. If left untreated, they can even lead to corneal perforation and endophthalmitis, resulting in permanent ocular damage. Our retrospective, descriptive and analytical study of 180 patients hospitalized for severe corneal abscess revealed risk factors such as ocular trauma, contact lens wear, ocular surgery and underlying medical conditions.

Keywords
Abscesses; Corneal; Bacterial; Fungal or viral; Treatment

Doi : https://doi.org/10.5281/zenodo.12687250

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Cite
HASSINA, S., BEKKAR, B., KRICHENE, M. A., HASNAOUI, I., HAZIL, Z., ROBBANA, L., AKKANOUR, Y., SERGHINI, L., & ABDALAH, E. H. (2024). Corneal abscesses: Diagnostic and therapeutic difficulties about 180 cases. International Journal of Science, Applications and Prosperity, 2(1), 64‑70.

Licence
Copyright @ by the authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

References
[1] Khidrou Fadhoullahi Oumarou Sambou, Abdoul Salam Youssoufou Souley, Case series about severe corneal abscesses: Epidemiological, clinical and microbiological study (about 37 cases), Annals of Medicine and Surgery, Volume 78, 2022, 103834, ISSN 2049-0801, https://doi.org/10.1016/j.amsu.2022.103834.
[2] Ohtani, Shinichiro, Kimiya Shimizu, Ryohei Nejima, Fumie Kagaya, Makoto Aihara, Takuya Iwasaki, Nobuyuki Shoji, and Kazunori Miyata. 2017. “Conjunctival Bacteria Flora of Glaucoma Patients during Long-Term Administration of Prostaglandin Analog Drops.” Investigative Ophthalmology and Visual Science 58 (10): 3991–96. doi:10.1167/iovs.1620853.
[3] Bourcier T, Thomas F, Borderie V, Chaumeil C, Laroche L. Bacterial keratitis: predisposing factors, clinical and microbiological review of 300 cases. Br J Ophthalmol. 2003 Jul;87(7):834-8. doi: 10.1136/bjo.87.7.834. PMID: 12812878; PMCID: PMC1771775.
[4] BOURCIER, T. Abcès de cornée: que faire ou ne pas faire en urgence. Réalités Ophtalmologiques, 2012, vol. 191, no 1, p. 1-3.
[5] J. Caliot, D. Guindolet, A. Ducasse, L. Andreoletti, C. Arndt, Apport diagnostique et thérapeutique des prélèvements microbiologiques des abcès de cornées avec critères de gravité au CHU de Reims entre 2012 et 2014, Journal Français d'Ophtalmologie, Volume 40, Issue 1, 2017, Pages 8-16, ISSN 0181-5512, https://doi.org/10.1016/j.jfo.2016.09.010.
[6] Hsin-Yu Liu, Hsiao-Sang Chu, I-Jong Wang, Wei-Li Chen, Fung-Rong Hu, Microbial Keratitis in Taiwan: A 20-Year Update, American Journal of Ophthalmology, Volume 205, 2019, Pages 74-81, ISSN 0002-9394, https://doi.org/10.1016/j.ajo.2019.03.023.
[7] R. Limaiem, F. Mghaieth, A. Merdassi, K. Mghaieth, A. Aissaoui, L. El Matri, Les abcès graves de la cornée : à propos de 100 cas, Journal Français d'Ophtalmologie, Volume 30, Issue 4, 2007, Pages 374-379, ISSN 0181-5512, https://doi.org/10.1016/S0181-5512(07)89607-0.
[8] Seck SM, Diakhaté M, Oulfath A, Sow MN, Dieng M, Gueye NN. Severe infectious keratitis in tropical environments: 118 cases collected over 10 years. Med Sante Trop. 2019 May 1;29(2):151-154. English. doi: 10.1684/mst.2019.0897. PMID: 31379339.
[9] Lalitha P, Manoharan G, Karpagam R, Prajna NV, Srinivasan M, Mascarenhas J, Das M, Porco TC, Lietman TM, Cevallos V, Keenan JD. Trends in antibiotic resistance in bacterial keratitis isolates from South India. Br J Ophthalmol. 2017 Feb;101(2):108-113. doi: 10.1136/bjophthalmol-2016-308487. Epub 2016 Apr 29. PMID: 27130916; PMCID: PMC7325411.
[10] BOURCIER, T., THOMAS, F., BORDERIE, V., et al. Bacterial keratitis: predisposing factors, clinical and microbiological review of 300 cases. British Journal of Ophthalmology, 2003, vol. 87, no 7, p. 834-838.
[11] JONES, B. R., MCGILL, J. I., et STEELE, A. D. Recurrent suppurative kerato-uveitis with loss of eye due to infection by Acanthamoeba castellani. Transactions of the ophthalmological societies of the United Kingdom, 1975, vol. 95, no 2, p. 210-213.
[12] Dahlgren, Matthew A, Ahila Lingappan, and Kirk R Wilhelmus. 2008. “The Clinical Diagnosis of Microbial Keratitis” 143 (6): 940–44. doi:10.1016/j.ajo.2007.02.030.
[13] Baum JL, Barza M, Weinstein L. Preferred routes of antibiotic administration in treatment of bacterial ulcers of the cornea. Int Ophthalmol Clin. 1973;13(4):31‑ 7.
[14] Gabison E. Kératites bactériennes : conduite à tenir et antibiothérapie. Réalités ophtalmologiques. févr 2013
[15] LORENZO-MORALES, Jacob, KHAN, Naveed A., et WALOCHNIK, Julia. An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment. Parasite, 2015, vol. 22.
[16] Butler TK, Males JJ, Robinson LP, Wechsler AW, Sutton GL, Cheng J, Taylor P, McClellan K. Six-year review of Acanthamoeba keratitis in New South Wales, Australia: 1997-2002. Clin Exp Ophthalmol. 2005 Feb;33(1):41-6. doi: 10.1111/j.1442-9071.2004.00911.x. PMID: 15670077.
[17] T. Bourcier, A. Sauer, V. Letscher-Bru, E. Candolfi, Kératites fongiques, Volume 1800, Issue 8, 10/2011, Pages 513-596, ISSN 0181-5512, http://dx.doi.org/10.1016/j.jfo.2011.03.001
[18] Emilie Frobert, Sonia Burrel, Sophie Ducastelle-Lepretre, Geneviève Billaud, Florence Ader, Jean Sébastien Casalegno, Viviane Nave, David Boutolleau, Mauricette Michallet, Bruno Lina, Florence Morfin, Resistance of herpes simplex viruses to acyclovir: An update from a ten-year survey in France, Antiviral Research, Volume 111, 2014, Pages 36-41, ISSN 0166-3542, https://doi.org/10.1016/j.antiviral.2014.08.013.